1. The medication memantine is used in the treatment of Alzheimer’s disease primarily by:
A) Blocking acetylcholine receptors
B) Enhancing GABAergic neurotransmission
C) Antagonizing glutamate receptors
D) Inhibiting serotonin reuptake
Answer: C) Antagonizing glutamate receptors
2. Which class of medications is commonly used for the treatment of bipolar disorder and works by stabilizing mood through various mechanisms, including inhibition of cyclic AMP?
A) Antidepressants
B) Benzodiazepines
C) Antipsychotics
D) Mood stabilizers (e.g., lithium)
Answer: D) Mood stabilizers (e.g., lithium)
3. The medication prazosin is sometimes used off-label in the treatment of:
A) Major depressive disorder
B) Generalized anxiety disorder
C) Post-traumatic stress disorder (PTSD)
D) Bipolar disorder
Answer: C) Post-traumatic stress disorder (PTSD)
4. Which neurotransmitter system is primarily affected by selective norepinephrine reuptake inhibitors (SNRIs), such as duloxetine?
A) Dopamine
B) Serotonin
C) Norepinephrine
D) Acetylcholine
Answer: C) Norepinephrine
5. The medication buspirone is used in the treatment of anxiety disorders primarily by:
A) Enhancing serotonin release
B) Blocking dopamine receptors
C) Acting as an agonist at serotonin (5-HT1A) receptors
D) Inhibiting norepinephrine reuptake
Answer: C) Acting as an agonist at serotonin (5-HT1A) receptors
6. Which medication is commonly used for the treatment of opioid use disorder and works by blocking opioid receptors?
A) Naltrexone
B) Methadone
C) Bupropion
D) Acamprosate
Answer: A) Naltrexone
7. The medication modafinil is used in the treatment of narcolepsy primarily by:
A) Enhancing GABAergic neurotransmission
B) Blocking serotonin reuptake
C) Inhibiting dopamine reuptake
D) Stimulating wakefulness-promoting centers in the brain
Answer: D) Stimulating wakefulness-promoting centers in the brain
8. Which class of medications is commonly used for the treatment of obsessive-compulsive disorder (OCD) and works by affecting serotonin reuptake?
A) Antipsychotics
B) Mood stabilizers
C) Benzodiazepines
D) Selective serotonin reuptake inhibitors (SSRIs)
Answer: D) Selective serotonin reuptake inhibitors (SSRIs)
9. The medication desvenlafaxine is classified as:
A) A selective serotonin reuptake inhibitor (SSRI)
B) A serotonin-norepinephrine reuptake inhibitor (SNRI)
C) A tricyclic antidepressant (TCA)
D) An atypical antidepressant
Answer: B) A serotonin-norepinephrine reuptake inhibitor (SNRI)
10. Which neurotransmitter system is primarily targeted by antipsychotic medications to alleviate cognitive deficits in schizophrenia?
A) Dopamine
B) Serotonin
C) Acetylcholine
D) Glutamate
Answer: C) Acetylcholine
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