Animal Toxicology MCQs January 8, 2026March 26, 2024 by u930973931_answers 49 min Score: 0 Attempted: 0/49 Subscribe 1. . What is animal toxicology? (A) The study of animals' diets (B) The study of animal behavior (C) The study of the effects of chemicals and substances on animals (D) The study of animal genetics 2. . Which of the following is NOT a route of exposure to toxic substances in animals? (A) Inhalation (B) Ingestion (C) Osmosis (D) Dermal contact 3. . What is the LD50 value in toxicology? (A) The lethal dose of a substance that kills 50% of the test population (B) The lowest detectable dose of a substance (C) The dose required for therapeutic effects (D) The dose at which toxicity is not observed 4. . Which of the following organs is commonly affected by toxic substances in animals? (A) Brain (B) Heart (C) Liver (D) Bones 5. . What is the primary purpose of acute toxicity testing in animal toxicology? (A) To assess long-term effects of toxins (B) To determine immediate harmful effects of toxins (C) To study chronic diseases (D) To evaluate genetic mutations 6. . Which of the following factors can influence the toxicokinetics of a substance in animals? (A) Temperature (B) Gender (C) Age (D) All of the above 7. . What is the NOAEL in toxicology? (A) The lowest observed adverse effect level (B) The highest dose without any observable adverse effects (C) The dose at which 50% of the test population is killed (D) The dose required for therapeutic effects 8. . Which type of toxicity testing assesses the effects of a substance on reproductive parameters in animals? (A) Genotoxicity testing (B) Subacute toxicity testing (C) Chronic toxicity testing (D) Reproductive toxicity testing 9. . What is the role of metabolism in toxicology? (A) To increase the toxicity of substances (B) To decrease the toxicity of substances (C) To facilitate excretion of toxins from the body (D) To inhibit detoxification processes 10. . Which of the following is a common method for determining acute toxicity in animal studies? (A) Subchronic toxicity testing (B) LD50 testing (C) Genotoxicity testing (D) Chronic toxicity testing 11. . What is the primary objective of subchronic toxicity testing in animal toxicology? (A) To study long-term effects of toxins (B) To assess immediate harmful effects of toxins (C) To determine carcinogenic potential (D) To evaluate reproductive toxicity 12. . Which of the following is NOT a type of acute toxicity test in animal toxicology? (A) LD50 test (B) Ames test (C) Draize test (D) Fixed-dose procedure 13. . How does the Ames test contribute to toxicological studies? (A) It assesses dermal toxicity (B) It evaluates reproductive toxicity (C) It measures mutagenicity of substances (D) It studies chronic toxicity 14. . What is the primary goal of chronic toxicity testing in animal studies? (A) To assess immediate harmful effects of toxins (B) To evaluate long-term effects of toxins (C) To determine reproductive toxicity (D) To measure genotoxicity 15. . Which of the following is a commonly used animal model for toxicology studies? (A) Drosophila melanogaster (B) E. coli bacteria (C) Zebrafish (D) Saccharomyces cerevisiae 16. . What is the primary objective of genotoxicity testing in animal toxicology? (A) To evaluate reproductive toxicity (B) To assess carcinogenic potential (C) To measure mutagenicity of substances (D) To study acute toxicity 17. . Which of the following is NOT a common parameter evaluated in genotoxicity testing? (A) DNA damage (B) Chromosomal aberrations (C) Organ weights (D) Mutagenic potential 18. . What is the primary purpose of a dose-response curve in toxicology? (A) To determine the LD50 of a substance (B) To assess reproductive toxicity (C) To study the relationship between dose and toxic effects (D) To measure genotoxicity 19. . Which of the following is a common method for assessing dermal toxicity in animal studies? (A) Inhalation exposure (B) Skin patch test (C) Intravenous injection (D) Oral gavage 20. . What is the significance of bioaccumulation in toxicology? (A) It refers to the rapid excretion of toxins from the body (B) It enhances detoxification processes (C) It leads to the accumulation of toxins in tissues over time (D) It reduces toxicity of substances 21. . Which of the following is a common sign of acute toxicity in animals? (A) Weight gain (B) Increased appetite (C) Rapid breathing (D) Normal behavior 22. . What is the primary goal of risk assessment in toxicology? (A) To determine the therapeutic effects of toxins (B) To evaluate the potential hazards of toxins to human health and the environment (C) To promote the use of toxic substances (D) To increase toxicity of substances 23. . Which of the following is a common method for assessing neurotoxicity in animal studies? (A) Morris water maze test (B) Forced swim test (C) Open field test (D) Elevated plus maze test 24. . What is the role of the liver in detoxification processes in animals? (A) To increase toxicity of substances (B) To inhibit metabolism of toxins (C) To facilitate excretion of toxins (D) To reduce bioavailability of toxins 25. . Which of the following is a common parameter evaluated in reproductive toxicity testing? (A) Liver function (B) Hormone levels (C) DNA damage (D) Chromosomal aberrations 26. . What is the primary purpose of acute dermal toxicity testing in animal studies? (A) To assess reproductive toxicity (B) To evaluate immediate harmful effects of skin exposure to toxins (C) To study genotoxicity (D) To measure chronic toxicity 27. . How does the Draize test contribute to toxicology studies? (A) It assesses carcinogenic potential (B) It measures genotoxicity (C) It evaluates dermal and ocular irritation (D) It studies reproductive toxicity 28. . Which of the following is a common method for assessing ocular toxicity in animal studies? (A) Skin patch test (B) Draize test (C) Intravenous injection (D) Oral gavage 29. . What is the primary purpose of a toxicokinetic study in animal toxicology? (A) To assess immediate harmful effects of toxins (B) To evaluate long-term effects of toxins (C) To study the absorption, distribution, metabolism, and excretion of toxins (D) To measure genotoxicity 30. . What is the primary objective of ecotoxicology? (A) To study the effects of chemicals on human health (B) To assess the impact of toxins on the environment and wildlife (C) To evaluate therapeutic effects of toxins (D) To promote the use of toxic substances 31. . Which of the following is a common method for assessing acute inhalation toxicity in animal studies? (A) Intravenous injection (B) Skin patch test (C) Whole-body exposure chambers (D) Oral gavage 32. . What is the role of the kidney in toxicology? (A) To increase bioavailability of toxins (B) To inhibit detoxification processes (C) To regulate pH levels in the body (D) To reduce toxicity of substances 33. . Which of the following is a commonly used model organism for studying developmental toxicity? (A) Rats (B) Frogs (C) Drosophila melanogaster (D) E. coli bacteria 34. . What is the primary objective of endocrine disruptor testing in toxicology? (A) To study the effects of toxins on the central nervous system (B) To evaluate reproductive and developmental toxicity (C) To assess dermal toxicity (D) To measure genotoxicity 35. . Which of the following is a common method for assessing subchronic inhalation toxicity in animal studies? (A) Intraperitoneal injection (B) Nasal instillation (C) Oral gavage (D) Whole-body exposure chambers 36. . What is the role of toxicokinetic modeling in toxicology studies? (A) To assess acute toxicity (B) To evaluate chronic toxicity (C) To predict how the body absorbs, distributes, metabolizes, and excretes toxins (D) To study reproductive toxicity 37. . Which of the following is a common parameter evaluated in immunotoxicity testing? (A) Neurotransmitter levels (B) Immune cell function (C) Liver enzyme activity (D) Kidney function 38. . What is the primary purpose of a chronic carcinogenicity study in animal toxicology? (A) To evaluate immediate harmful effects of toxins (B) To study long-term effects of toxins on cancer development (C) To assess reproductive toxicity (D) To measure genotoxicity 39. . Which of the following is a common method for assessing subacute oral toxicity in animal studies? (A) Intravenous injection (B) Skin patch test (C) Oral gavage (D) Whole-body exposure chambers 40. . What is the significance of using in vitro models in toxicology studies? (A) They replace the need for animal testing (B) They evaluate chronic toxicity (C) They assess reproductive toxicity (D) They study genotoxicity 41. . Which of the following is a common method for assessing immunotoxicity in animal studies? (A) T cell receptor assay (B) Liver function test (C) Blood glucose measurement (D) Body weight monitoring 42. . What is the primary objective of neurotoxicity testing in toxicology? (A) To study the effects of toxins on the liver (B) To assess reproductive toxicity (C) To evaluate the impact of toxins on the central nervous system (D) To measure genotoxicity 43. . Which of the following is a common method for assessing developmental toxicity in animal studies? (A) Morris water maze test (B) Forced swim test (C) Teratogenicity test (D) Open field test 44. . What is the role of the gastrointestinal tract in toxicology? (A) To increase bioavailability of toxins (B) To inhibit detoxification processes (C) To absorb nutrients and excrete toxins (D) To reduce toxicity of substances 45. . Which of the following is a common parameter evaluated in ecotoxicology studies? (A) Blood pressure (B) Water quality (C) Immune cell function (D) Hormone levels 46. . What is the primary objective of dermal sensitization testing in animal toxicology? (A) To assess reproductive toxicity (B) To evaluate immediate harmful effects of skin exposure to toxins (C) To study genotoxicity (D) To measure chronic toxicity 47. . Which of the following is a common method for assessing teratogenicity in animal studies? (A) Inhalation exposure (B) Dermal application (C) Oral gavage (D) Pregnancy testing 48. . What is the significance of using biomarkers in toxicology studies? (A) They replace the need for animal testing (B) They assess acute toxicity (C) They indicate exposure or effects of toxins in biological systems (D) They evaluate reproductive toxicity 49. . Which of the following is a common parameter evaluated in cardiotoxicity testing? (A) Kidney function (B) Liver enzyme activity (C) Heart rate and rhythm (D) Blood glucose concentration