Immunology — MCQs

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1. Which cells are primarily responsible for antibody production?





2. Which type of immunity is provided by vaccination?





3. Which antibody is the first produced in a primary immune response?





4. Which of the following acts as antigen-presenting cells?





5. The major histocompatibility complex (MHC) in humans is known as:





6. Which type of hypersensitivity is mediated by IgE?





7. Which cells are known as “killer cells”?





8. The complement system is part of:





9. Which cytokine is also known as endogenous pyrogen?





10. The antibody present in breast milk is:





11. Which cells are primarily affected in HIV infection?





12. Which organ is the site of T-cell maturation?





13. Antibodies are also called:





14. Which immunoglobulin can cross the placenta?





15. Which hypersensitivity reaction is also called delayed-type hypersensitivity?





16. Which is the most abundant antibody in serum?





17. Which cells are professional antigen-presenting cells?





18. Which cytokine is responsible for B-cell proliferation?





19. Herd immunity is achieved through:





20. Which cells release histamine during allergic reactions?





21. Which antibody is associated with allergic responses?





22. Which organ is the primary site of B-cell development?





23. The process of coating pathogens with antibodies for phagocytosis is called:





24. Which cells are also called “natural killer cells”?





25. Which part of the antibody binds to the antigen?





26. Passive immunity differs from active immunity because it:





27. Which of the following is an autoimmune disease?





28. Which immunoglobulin is pentameric in structure?





29. Which organ filters blood and helps in immune response?





30. The coating of virus by antibody to prevent attachment to host cells is called:





31. Which cytokine is also called T-cell growth factor?





32. Which of the following is the first line of defense in innate immunity?





33. Which type of immunity is acquired from mother to child through placenta?





34. Which immune cells are known as “helper cells”?





35. The process of programmed cell death is called:





36. Which immune organ shrinks with age?





37. Which complement pathway is activated by antigen–antibody complex?





38. Which immunoglobulin is secreted in tears and saliva?





39. Which cells are known as “big eaters”?





40. Which part of the immune system provides memory response?





41. Which type of hypersensitivity reaction is contact dermatitis?





42. Which antibody is found in highest concentration in serum?





43. Which is the most effective antigen-presenting cell?





44. Which organ is the site of lymphocyte filtration and activation?





45. The process of antibody binding to multiple antigens and forming clumps is called:





46. Which cytokine is mainly involved in inflammation?





47. Which cells kill virus-infected cells without prior sensitization?





48. Which type of immunity is provided by antitoxins?





49. Which molecule on T-cells recognizes MHC class II?





50. Which cytokine is most important for antiviral defense?





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