Structural Biology — MCQs

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1. The study of the 3D structure of biological macromolecules is called:





2. The primary structure of a protein refers to:





3. Alpha helix and beta sheet are examples of:





4. The 3D arrangement of all atoms in a single polypeptide chain is called:





5. The association of multiple polypeptide chains is called:





6. The alpha helix in proteins is stabilized mainly by:





7. The beta sheet structure in proteins can be:





8. The disulfide bond is formed between:





9. The Ramachandran plot shows:





10. X-ray crystallography is commonly used to determine:





11. The main limitation of X-ray crystallography is:





12. Cryo-electron microscopy is especially useful for:





13. Nuclear Magnetic Resonance (NMR) spectroscopy is mainly used to study:





14. The hydrophobic effect is critical in:





15. Chaperone proteins assist in:





16. The central dogma of molecular biology involves:





17. The major structural component of cell membranes is:





18. Collagen is an example of a protein with:





19. Hemoglobin is an example of:





20. The protein secondary structure first described by Linus Pauling is:





21. DNA double helix was discovered by:





22. Base pairing in DNA is stabilized by:





23. In DNA, adenine pairs with:





24. In RNA, adenine pairs with:





25. The diameter of B-DNA double helix is approximately:





26. Nucleosomes consist of DNA wrapped around:





27. The structural motif “zinc finger” is commonly found in:





28. A protein domain is:





29. The Levinthal paradox refers to:





30. Hydrogen bonds in protein alpha helices are formed between:





31. The unit cell is a concept in:





32. Glycosylation of proteins usually occurs in:





33. Membrane proteins can be classified as:





34. Myoglobin differs from hemoglobin by being:





35. Enzyme active sites are usually located in:





36. The enzyme-substrate interaction model originally proposed is called:





37. The enzyme-substrate model refined later is:





38. The quaternary structure of a protein is stabilized mainly by:





39. Intrinsically disordered proteins lack:





40. Prions are misfolded forms of:





41. The structural motif “helix-turn-helix” is important in:





42. Collagen is rich in which amino acid?





43. Protein crystallography data are usually represented in:





44. Circular dichroism spectroscopy is used to study:





45. Ribozymes are:





46. The quaternary structure of ATP synthase includes:





47. Hydrogen bonds in DNA are stronger when base pairs are:





48. The B-form DNA has a right-handed helix with how many base pairs per turn?





49. The A-form of DNA is usually observed in:





50. Z-DNA is characterized by:





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