Genetics — MCQs January 8, 2026August 20, 2025 by u930973931_answers 50 Score: 0 Attempted: 0/50 Subscribe 1. Who is considered the father of Genetics? (A) Charles Darwin (B) Gregor Mendel (C) Alfred Hershey (D) Thomas Morgan 2. Which plant did Mendel use in his experiments? (A) Wheat (B) Maize (C) Pea plant (D) Barley 3. The physical appearance of an organism is called: (A) Genotype (B) Phenotype (C) Allele (D) Trait 4. What is the basic unit of heredity? (A) DNA (B) Gene (C) Chromosome (D) Protein 5. Alternative forms of a gene are called: (A) Loci (B) Alleles (C) Traits (D) Genomes 6. Homozygous condition means: (A) Different alleles (B) Same alleles (C) Dominant allele only (D) Recessive allele only 7. Heterozygous condition means: (A) Identical alleles (B) Two different alleles (C) Only recessive genes (D) Only dominant genes 8. The law of segregation was given by: (A) Charles Darwin (B) Watson (C) Mendel (D) Morgan 9. A cross between individuals with one differing trait is: (A) Dihybrid cross (B) Monohybrid cross (C) Back cross (D) Test cross 10. Incomplete dominance is seen in: (A) Pea plants (B) Snapdragon flowers (C) Maize plants (D) Wheat 11. Who discovered the structure of DNA? (A) Mendel and Darwin (B) Watson and Crick (C) Hershey and Chase (D) Morgan and Sturtevant 12. DNA is made up of repeating units called: (A) Amino acids (B) Nucleotides (C) Monosaccharides (D) Fatty acids 13. Which nitrogen base pairs with adenine in DNA? (A) Cytosine (B) Thymine (C) Guanine (D) Uracil 14. Which nitrogen base pairs with adenine in RNA? (A) Cytosine (B) Thymine (C) Guanine (D) Uracil 15. The law of independent assortment was given by: (A) Mendel (B) Watson (C) Crick (D) Darwin 16. The total genetic material of an organism is called: (A) Chromosome (B) Gene pool (C) Genome (D) Proteome 17. Sex-linked inheritance was discovered by: (A) Darwin (B) Morgan (C) Mendel (D) Watson 18. In humans, sex is determined by: (A) X chromosomes only (B) Y chromosome (C) Autosomes (D) Z chromosomes 19. Color blindness is an example of: (A) Autosomal dominance (B) Autosomal recessive (C) X-linked recessive (D) Y-linked trait 20. Which is the smallest unit of genetic information? (A) Codon (B) Chromosome (C) Gene (D) Genome 21. Crossing over occurs during: (A) Prophase I of meiosis (B) Metaphase of mitosis (C) Anaphase of meiosis II (D) Telophase of mitosis 22. Who introduced the concept of mutation? (A) Hugo de Vries (B) Darwin (C) Mendel (D) Lamarck 23. The process of making RNA from DNA is called: (A) Translation (B) Replication (C) Transcription (D) Transformation 24. The process of protein synthesis from RNA is called: (A) Replication (B) Transcription (C) Translation (D) Transduction 25. Which organelle is known as the site of protein synthesis? (A) Lysosome (B) Ribosome (C) Golgi body (D) Nucleus 26. The human genome contains how many chromosomes? (A) 22 pairs (B) 23 pairs (C) 24 pairs (D) 21 pairs 27. Mutations in DNA can be caused by: (A) Radiation (B) Chemicals (C) Viruses (D) All of the above 28. A change in a single base pair in DNA is called: (A) Chromosomal mutation (B) Point mutation (C) Frame shift mutation (D) Gene duplication 29. The Human Genome Project was completed in: (A) 2000 (B) 2003 (C) 1999 (D) 2005 30. Sickle cell anemia is caused by: (A) Chromosomal deletion (B) Substitution mutation (C) Frameshift mutation (D) Gene duplication 31. Which type of RNA carries amino acids? (A) mRNA (B) rRNA (C) tRNA (D) snRNA 32. Which type of RNA carries genetic code from DNA? (A) tRNA (B) mRNA (C) rRNA (D) snRNA 33. Who discovered linkage in genes? (A) Mendel (B) Morgan (C) Darwin (D) Hershey 34. Which enzyme unzips DNA during replication? (A) DNA helicase (B) DNA ligase (C) DNA polymerase (D) RNA polymerase 35. Okazaki fragments are formed on: (A) Leading strand (B) Lagging strand (C) Both strands (D) Chromosomes only 36. The three-base sequence on mRNA is called: (A) Anticodon (B) Codon (C) Intron (D) Exon 37. The three-base sequence on tRNA is called: (A) Anticodon (B) Codon (C) Exon (D) Intron 38. A gene that masks the effect of another gene is: (A) Recessive (B) Dominant (C) Epistatic (D) Suppressor 39. A recessive allele is expressed when: (A) Paired with dominant allele (B) Present in heterozygous (C) Present in homozygous condition (D) In sex-linked traits only 40. The study of chromosomes is called: (A) Cytogenetics (B) Genomics (C) Proteomics (D) Karyology 41. Which technique is used to amplify DNA? (A) ELISA (B) PCR (C) Gel electrophoresis (D) Northern blot 42. Gel electrophoresis separates DNA based on: (A) Color (B) Size and charge (C) Shape (D) Base sequence 43. Which chromosome is called the “sex chromosome”? (A) Chromosome 21 (B) X and Y chromosomes (C) Chromosome 22 (D) Chromosome 1 44. Down’s syndrome is caused by: (A) Trisomy 21 (B) Trisomy 18 (C) Monosomy X (D) Deletion of 22 45. Which disease is linked to defective hemoglobin? (A) Hemophilia (B) Sickle cell anemia (C) Color blindness (D) Albinism 46. Which is the universal genetic code start codon? (A) AUG (B) UAA (C) UGA (D) UAG 47. Which bonds hold DNA strands together? (A) Ionic bonds (B) Hydrogen bonds (C) Peptide bonds (D) Covalent bonds 48. Which organelle contains its own DNA? (A) Ribosome (B) Golgi body (C) Mitochondria (D) Lysosome 49. The region of DNA that codes for proteins is called: (A) Intron (B) Exon (C) Enhancer (D) Promoter 50. The technique of transferring genes between organisms is called: (A) Cloning (B) Genetic engineering (C) Cross-breeding (D) Hybridization