Bioinformatics – MCQs September 2, 2025 by u930973931_answers 50 Score: 0 Attempted: 0/50 Subscribe 1. What is the main focus of bioinformatics? (A) Food preservation (B) Application of computational tools to biological data (C) Hospital management (D) Agricultural production 2. Which of the following is the primary data used in bioinformatics? (A) Genomic and protein sequence data (B) Hospital bills (C) Patient diet records (D) Medical certificates 3. The Human Genome Project is an example of: (A) Bioinformatics application (B) Hospital research project (C) Engineering design (D) Agricultural study 4. Which database is used for storing nucleotide sequences? (A) GenBank (B) PDB (C) Swiss-Prot (D) SCOP 5. The Protein Data Bank (PDB) mainly stores: (A) 3D structures of proteins and nucleic acids (B) Hospital reports (C) Patient names (D) Bacterial growth charts 6. BLAST is a tool used for: (A) Sequence alignment and similarity search (B) Hospital billing (C) Drug pricing (D) Food quality testing 7. FASTA format is commonly used for: (A) Storing biological sequences (B) Hospital records (C) Patient reports (D) Food recipes 8. Which of the following is an application of bioinformatics? (A) Drug discovery and design (B) Road construction (C) Hospital cleaning (D) Car manufacturing 9. Multiple sequence alignment is used to: (A) Identify conserved regions in DNA/proteins (B) Calculate patient expenses (C) Record hospital staff duty (D) Plan agriculture 10. In bioinformatics, homology refers to: (A) Similarity due to shared ancestry (B) Similar hospital facilities (C) Identical economic conditions (D) Same hospital bills 11. Which software is widely used for phylogenetic analysis? (A) MEGA (B) Photoshop (C) MS Word (D) AutoCAD 12. The study of proteins using bioinformatics tools is called: (A) Proteomics (B) Genomics (C) Transcriptomics (D) Metabolomics 13. Which bioinformatics tool predicts protein secondary structure? (A) PSIPRED (B) BLAST (C) FASTA (D) GenBank 14. NCBI stands for: (A) National Center for Biotechnology Information (B) National Center for Business Information (C) New College for Bioinformatics Institute (D) National Center for Basic Integration 15. ClustalW is used for: (A) Multiple sequence alignment (B) Protein folding (C) Hospital statistics (D) Drug pricing 16. A genome is defined as: (A) Complete set of DNA in an organism (B) Hospital staff list (C) Patient’s medical record (D) Food storage system 17. Protein modeling in bioinformatics is mainly used for: (A) Predicting 3D structure of proteins (B) Storing hospital data (C) Preparing patient charts (D) Agricultural mapping 18. Which database contains protein sequence information? (A) UniProt (B) GenBank (C) EMBL (D) DDBJ 19. Sequence annotation refers to: (A) Identifying functional elements in a sequence (B) Recording hospital staff names (C) Creating patient bills (D) Labeling drugs in pharmacies 20. The process of comparing biological sequences is known as: (A) Sequence alignment (B) Data mining (C) Billing system (D) Hospital scheduling 21. A phylogenetic tree represents: (A) Evolutionary relationship among species (B) Hospital management structure (C) Agricultural crop growth (D) Economic growth 22. Bioinformatics plays a key role in: (A) Personalized medicine (B) Road building (C) Food delivery (D) Transport system 23. Swiss-Prot is a database of: (A) Manually curated protein sequences (B) Hospital beds (C) Patient reports (D) X-ray images 24. The study of all RNA transcripts is known as: (A) Transcriptomics (B) Proteomics (C) Metabolomics (D) Pharmacogenomics 25. Which file format is common for protein structure data? (A) PDB (B) TXT (C) DOCX (D) PDF 26. Hidden Markov Models (HMMs) are used in bioinformatics for: (A) Protein sequence analysis (B) Hospital data storage (C) Economic predictions (D) Food supply chain 27. Which of the following is a high-throughput technique in bioinformatics? (A) Next-generation sequencing (NGS) (B) Handwriting analysis (C) Manual lab testing (D) X-ray imaging 28. Functional genomics is mainly concerned with: (A) Gene expression and function (B) Hospital expansion (C) Drug pricing (D) Road networks 29. Which algorithm is commonly used for sequence alignment? (A) Needleman–Wunsch (B) Dijkstra’s algorithm (C) Quick sort (D) Binary search 30. Pharmacogenomics studies: (A) Influence of genes on drug response (B) Hospital food delivery (C) Patient room allocation (D) Nurse scheduling 31. The field integrating biology, computer science, and mathematics is: (A) Bioinformatics (B) Geology (C) Pharmacology (D) Sociology 32. KEGG is a database for: (A) Metabolic pathways and gene functions (B) Patient information (C) Hospital staff records (D) Agriculture mapping 33. DNA microarrays are used for: (A) Studying gene expression (B) Measuring hospital bills (C) Recording staff data (D) Blood typing 34. Homology modeling is used to: (A) Predict protein 3D structure based on known templates (B) Prepare patient bills (C) Map hospital staff duties (D) Analyze agricultural land 35. DDBJ is a database located in: (A) Japan (B) USA (C) UK (D) Germany 36. The study of all small molecules in a biological system is called: (A) Metabolomics (B) Transcriptomics (C) Proteomics (D) Genomics 37. PSI-BLAST is mainly used for: (A) Detecting distant protein relationships (B) Managing hospital bills (C) Recording nurse duty schedules (D) Agricultural irrigation 38. Sequence motifs represent: (A) Conserved regions with biological significance (B) Patient medical records (C) Hospital budgets (D) Blood test reports 39. The EMBL database is based in: (A) Europe (B) USA (C) China (D) India 40. A key challenge in bioinformatics is: (A) Managing large biological datasets (B) Managing hospital cafeterias (C) Hiring hospital staff (D) Road construction projects 41. Which programming language is widely used in bioinformatics? (A) Python (B) C++ (C) Java (D) All of the above 42. Structural bioinformatics focuses on: (A) 3D structure of biomolecules (B) Patient health records (C) Hospital management (D) Blood donation drives 43. Genome annotation involves: (A) Identifying coding and non-coding regions in DNA (B) Measuring patient height (C) Recording staff duties (D) Printing hospital bills 44. Which of the following is NOT a bioinformatics database? (A) GenBank (B) Swiss-Prot (C) Facebook (D) PDB 45. Phylogenomic studies combine: (A) Phylogenetics and genomics (B) Economics and sociology (C) Hospitals and tourism (D) Agriculture and engineering 46. Next-generation sequencing has revolutionized: (A) Genomic research and medicine (B) Road construction (C) Hospital food services (D) Economic growth 47. Which technique is used to predict gene function? (A) Comparative genomics (B) Hospital survey (C) Food chemistry (D) Road mapping 48. Systems biology integrates: (A) Biological data to understand complex systems (B) Hospital data for budgeting (C) Road transport data (D) Food distribution data 49. The FASTA algorithm was developed for: (A) Rapid sequence alignment (B) Printing hospital records (C) Calculating patient expenses (D) Agricultural yield prediction 50. An important application of bioinformatics in healthcare is: (A) Identifying disease-related genes (B) Expanding hospital buildings (C) Organizing patient rooms (D) Staff promotions