Bioinformatics — MCQs

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1. Which of the following is the primary database for nucleotide sequences?





2. The Protein Data Bank (PDB) mainly stores:





3. Which algorithm is most commonly used for sequence alignment?





4. BLAST is used for:





5. FASTA format is commonly used for:





6. Which tool is used for multiple sequence alignment?





7. The Human Genome Project was completed in:





8. In bioinformatics, annotation refers to:





9. UniProt is a database for:





10. Which programming language is most widely used in bioinformatics?





11. KEGG database is primarily used for:





12. The Needleman–Wunsch algorithm is used for:





13. Smith–Waterman algorithm is used for:





14. Phylogenetic trees represent:





15. Hidden Markov Models (HMMs) are used in bioinformatics for:





16. In databases, “redundancy” refers to:





17. Which file format is used for protein structures?





18. What does BLAST stand for?





19. Molecular docking is used to study:





20. Transcriptomics deals with the study of:





21. The central dogma of molecular biology describes the flow of information from:





22. Structural bioinformatics deals with:





23. Which database provides information about protein families and domains?





24. Which bioinformatics tool is used for primer design?





25. A phylogenetic tree with a single common ancestor is called:





26. The process of converting raw sequence data into meaningful biological information is called:





27. Which database is specialized in metabolic pathways?





28. Which of the following is an application of bioinformatics?





29. The FASTQ file format is used in:





30. Which visualization tool is commonly used for protein 3D structures?





31. Homology modeling is used to:





32. The main role of transcriptomics is to study:





33. Which database contains curated protein-protein interactions?





34. Which algorithm is widely used in BLAST?





35. The reference sequence database maintained by NCBI is called:





36. Protein secondary structure includes:





37. Microarray technology is used to study:





38. Which term describes similarity due to common ancestry?





39. The process of predicting a protein’s 3D structure from its sequence is called:





40. Which software is used for sequence alignment visualization?





41. Molecular dynamics simulations are used to:





42. In bioinformatics, ORF stands for:





43. Which technique is commonly used for protein structure determination?





44. RNA-Seq is mainly used for:





45. Comparative genomics involves:





46. Which of the following is NOT a primary database?





47. A database of protein families based on multiple sequence alignment is:





48. A hidden Markov model is best applied in:





49. Which is a secondary database that compiles information from primary sources?





50. Which approach is widely used in drug discovery using bioinformatics?





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